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Nicotinamide Mononucleotide (NMN)

Molecular Formula: C11H15N2O8P
Molecular Weight: 334.22
Physical Appearance: White powder
pH of Solution: 3.0-4.0 (100mg/mL water)


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Nicotinamide mononucleotide (NMN) is a ribonucleotide containing of the nitrogenous base nicotinamide, a ribose sugar, and a phosphate group (1). NMN is a direct precursor of the coenzyme nicotinamide adenine dinucleotide (NAD)(2). NMN biosynthesis pathways vary in eukaryotes and prokaryotes. NMN plays a role in cardiac and cerebral ischemia, Alzheimer's disease, diabetes, obesity, cancer and aging (3). Scientific applications of this product include pharmacological studies and RNA aptamer binding motif analysis.


1. National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 14180, Nicotinamide mononucleotide. Retrieved October 18, 2022 from https://pubchem.ncbi.nlm.nih.gov/compound/Nicotinamide-mononucleotide.

2. Nakamura M, Bhatnagar A, Sadoshima J. Overview of pyridine nucleotides review series. Circ Res. 2012 Aug 17;111(5):604-10. doi: 10.1161/CIRCRESAHA.111.247924. PMID: 22904040; PMCID: PMC3523884.

3. Poddar SK, Sifat AE, Haque S, Nahid NA, Chowdhury S, Mehedi I. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019 Jan 21;9(1):34. doi: 10.3390/biom9010034. PMID: 30669679; PMCID: PMC6359187..

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