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MERS Spike Protein RBD

Recombinant MERS Spike Protein RBD (377-588) was expressed in CHO cells using a C-terminal human IgG1 Fc tag.


10 ug 20 ug 50 ug 100 ug

$ 100


The Middle East respiratory syndrome coronavirus (MERS-CoV) has caused the MERS outbreak that first originated in Saudi Arabia, but since has spread to other countries around the world (1). The spike glycoprotein (S) of coronavirus belongs to the type I transmembrane protein containing two subunits (2), S1 and S2, which is known to be the key component to bind with host cells through interaction with dipeptidyl peptidase 4 (DPP4) (3). MERS-CoV can recognize DPP4 through its receptor binding domain (RBD) of S1 to initiate viral infection in humans (2).

Gene Aliases:

MERS coronavirus S1, coronavirus S2, coronavirus spike, cov spike, ncov S1, ncov S2, ncov RBD, Spike RBD, RBD

Genebank Number:


Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 90mM glycine.


1. Mohd H, et al: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir. Viral J. 2016, 13: 87.

2. Lu G, et al: Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature. 2013, 500: 227-231.

3. Al-Tawfiq et al: Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) Infection. Emerging Infectious Diseases. 2014, 185-190.

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Acute Respiratory Distress Syndrome , Cardiovascular Disease, Cell Cycle, Cellular Stress, COVID19, Gastrointestinal Diseases , Infectious Diseases , Inflammation, Lung Diseases , Metabolic Disorder, Neurobiology, severe acute respiratory syndrome coronavirus 2 , Virology